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CENTER FOR CANCER RESEARCH
CENTER FOR CANCER RESEARCH

Role of somatic cancer mutations in human protein lysine methyltransferases  - ScienceDirect
Role of somatic cancer mutations in human protein lysine methyltransferases - ScienceDirect

berry (@berry46566269) / Twitter
berry (@berry46566269) / Twitter

PDF) Targeting Histone Lysine Methylation in Cancer
PDF) Targeting Histone Lysine Methylation in Cancer

An Alternative Approach to ChIP-Seq Normalization Enables Detection of  Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2  Inhibition | PLOS ONE
An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition | PLOS ONE

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - ScienceDirect
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - ScienceDirect

Full article: Epigenetic modification in chromatin machinery and its  deregulation in pediatric brain tumors: Insight into epigenetic therapies
Full article: Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

Luke B. Hesson · Antonia L. Pritchard Editors
Luke B. Hesson · Antonia L. Pritchard Editors

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

Targeting histone lysine methylation in cancer - ScienceDirect
Targeting histone lysine methylation in cancer - ScienceDirect

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

EZH2 Inhibitor Efficacy in Non-Hodgkin's Lymphoma Does Not Require  Suppression of H3K27 Monomethylation - ScienceDirect
EZH2 Inhibitor Efficacy in Non-Hodgkin's Lymphoma Does Not Require Suppression of H3K27 Monomethylation - ScienceDirect

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - ScienceDirect
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - ScienceDirect

Cancer-epigenetic function of the histone methyltransferase KMT2D and  therapeutic opportunities for the treatment of KMT2D-deficient tumors |  Oncotarget
Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors | Oncotarget

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling  in KMT2D Mutant Melanoma. - Abstract - Europe PMC
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. - Abstract - Europe PMC

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - Journal of Biological Chemistry
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - Journal of Biological Chemistry

IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape
IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape

Vulnerabilities of Mutant SWI/SNF Complexes in Cancer: Cancer Cell
Vulnerabilities of Mutant SWI/SNF Complexes in Cancer: Cancer Cell

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer - ScienceDirect
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer - ScienceDirect